This evidence review was conceptualised and authored by Prostate Cancer UK. It provides a comprehensive analysis of recent evidence on overdiagnosis within the MRI era and explores potential strategies to reduce its impact on patients and clinical practice. An abridged version of this review forms part of the APPG report 'Reducing the risks: Overdiagnosis and overtreatment in today's prostate cancer pathway'.

This document should be referenced as follows: Prostate Cancer UK, 2025. Prostate cancer overdiagnosis in the MRI era: an evidence review, Natalia Norori, on behalf of the Data & Evidence team at Prostate Cancer UK.

Please contact dataandevidence@prostatecanceruk.org for any questions, comments or feedback on the report